Yonesawara Hospital is a single-player exploration horror game from the first-person perspective.

The game focuses on the search for the abandoned hospital "Yonesawara Hospital", and by finding various clues, the truth about what happened at the hospital will be revealed.

In 1978, a doctor's office was closed due to the sudden disappearance of the director. Ten years later, a phone call to an investigator sets the story in motion. What happened to the director? The investigators go to the abandoned clinic to track down the disappearances that occurred in the past.