Wolfenstein II: The New Colossus is the eleventh installment of the Wolfenstein series and a sequel to the 2014's Wolfenstein: The New Order. The game follows the main protagonist, William Joseph "B.J." Blazkowicz, in his efforts to ignite a Second American Revolution.

The game is played from a first-person perspective and most of its levels are navigated on foot. The story is arranged in chapters, which players complete in order to progress. A binary choice in the prologue alters the game's entire storyline; some characters and small plot points are replaced throughout the timelines. The game features a variety of weapons, most of which can be dual wielded. A cover system is also present.

After the events of the first game, in which General Wilhelm "Deathshead" Strasse is eliminated, the Kreisau Circle retrieves the critically injured William "B.J." Blazkowicz from Deathshead's fortress before destroying it with a nuclear cannon. He. is still recovering from his wounds on a stolen U-boat called Eva’s Hammer.

Suddenly, the U-boat is attacked by Frau Engel, a sadistic Nazi commander and captures Caroline. Blazkowicz devises a plan to get himself captured and taken to Engel's airship, the Ausmerzer, which is suspending the U-boat above water. Engel tries to get her daughter Sigrun to decapitate Caroline, but the former refuses, resulting in Engel killing Caroline herself. Sigrun has a change of heart and tackles Engel, allowing Blazkowicz to use Caroline's armor. Blazkowicz disconnects Eva's Hammer from the Ausmerzer and flees back to the U-boat with Caroline's body.

Now armed with Caroline's armor, B.J is ready to return stateside, avenge his friends, kill every Nazi in sight and spark the second American Revolution.