Two Crude Dudes is a 1991 beat 'em up arcade game produced by Data East. The game was later ported to the Sega Genesis in 1992. Outside Japan, the port was released under the name Two Crude Dudes. In Japan, the game was titled: Crude Buster.

In the game, players control one of two mercenaries hired by the U.S. government to stop the terrorist organization "Big Valley". Their objective is to retake control of a ruined New York City from Big Valley after a nuclear explosion the group caused.

The year is 20XX. A nuclear weapon combined with chemicals made by a mad scientist explodes in the city of New York, turning many of the city's inhabitants into savage mutants willing to obey any command. The scientist establishes an organization he calls "Big Valley," consisting of these mutants and many advanced military weapons. He orders them to take the ruined city by force and refuse to let anyone enter. Desperate, the US government hires the help of two super-powered mercenaries to enter the city and eliminate the villains occupying it.