Sweet Tooth To Go is Pogo.com's own variant of Bejeweled, developed by the original creators of the game. The gameplay is identical to Bejeweled, however it has a new theme. Instead of different kinds of jewels, the player now has to match sweets of different kinds.

The game takes place on an 8x8 grid of tiles. The player's task is to match three or more tiles of the same sort. This is done by swaping adjacent tiles. Once a match has been made, the tiles disappear and other tiles drop down to fill their place, possibly creating a chain reaction of more matches.

Sweet Tooth To Go has two game modes, normal mode and time trial mode. The difference is that the normal mode lets the player take as long time as he wishes, while the time trial mode has a bonus bar that continually counts down towards zero. The bonus bar is replenished when the player makes matches.