Samurai Jack in Desert Quest was a Macromedia Shockwave Toonami game that was available to play on cartoonnetwork.com beginning in 2002. However, the game did not appear on toonami.com until 2004. The game is no longer available at cartoonnetwork.com, but has been archived by fans.

In this 3-level game, track down and defeat Aku to recover the sacred crystal. Aku and his minions have attacked one of the local villages. Some of the villagers are badly injured. Among them is a little girl - Kiri - whose life hangs by a very thin thread. The only thing that can save her is the sacred crystal, believed to heal all wounds. Jack takes it upon himself to venture into the desert and find the crystal, which has been taken by Aku's creatures.