Resistance: Burning Skies is a unique Resistance experience developed specifically for PS Vita that takes full advantage of the system's dual analog sticks and features an all-new hero and story written by William C. Dietz, author of Resistance: The Gathering Storm and Resistance: A Hole in the Sky.

The story begins with Tom Riley, along with Engine 174, driving through Staten Island. They eventually arrive at a burning power station. Not long after entering the station, Tom is seperated from his fellow firemen, when he falls through a weak floorboard. After making his way back up the station, Tom witnesses a fellow firemen get abducted and killed by a Longleg. Startled, Tom gathers his wits, and fights his way to fellow firefighter Smitty, the only other survivor. The two eventually make it out of the station, and into the war-torn streets of Staten Island.