Puzzle League (also known as Panel de Pon Multiboot) has been released with several Panel de Pon games. It was first released on February 7, 2003 in the Nintendo Puzzle Collection alongside Panel de Pon (GCN). This game would later get released internationally in English under the localized Puzzle League name in the GBA compilation Dr. Mario & Puzzle League alongside Dr. Mario.

This the only Panel de Pon fairy aesthetic game to be officially translated in English (Since Panel de Pon (SFC) was not translated in the Nintendo Switch Online release as it simply reuses the Japanese ROM), albeit with it's title screen replaced. The game features Pupuri, the Flower Fairy Mascot who makes an appearance in both this game and Panel de Pon (Nintendo Puzzle Collection).