Nazo Puyo 2 is a Puzzle game, developed by Compile and published by Sega, which was released in Japan in 1993 and is the second Nazo Puyo title for the Game Gear.

Like its predecessor, Nazo Puyo 2 is a spinoff that consists entirely of single-player puzzles. The game features 100 new puzzles and removes the previous game's password system in favor of battery-backed storage; otherwise, the two games are nearly identical.