Your life as a high school student has been going pretty smoothly so far. You and your childhood friend Mariya have been making the best of it, until one day, you hear about two strange creatures escaping from a lab. You think nothing too much of it until one day, you come across two mysterious girls on your way home from school one day that clearly seemed distressed. Being the good samaritan you are, you decide to take them home and give them something to eat and you learn that their names are Maki and Ayano.

But later that night when moonlight shines through the windows, they suddenly transform revealing that they are wolf girls! It’s that moment you realize that they are the creatures that escaped from the lab! In the heat of things, Mariya gets bit by one of them and she starts turning into a wolf girl… Will you be able to solve the mystery of the wolf girls and help your childhood friend!