Adam Warlock warns the earth of the Infinity Stones being sought by Magus, and so earth's heroes divide into teams to collect each Gem. These gems are placed into the possession of The Enchantress, MODOK, Selene, Ronan the Accuser, and Russia's superheroes.

In the end, the gathering of the heroes is what allows Magus to collect them all and try to wipe the floor with them.

Marvel Infinity War is a module created by ZVitor, based on the Marvel Comics Universe, and is a sequel to the Marvel First Alliance series. The game has 80 playable characters plus one secret character. There are also over 36 bosses to contend with. The game uses a six-button control scheme. Each character has at least one special move and an ultra move. There are also many special assist characters to summon.