Marathon 2: Durandal is the sequel to the first Marathon. Although the engine is similar to Doom in most respects (2.5D maps, bitmap sprites instead of polygons, etc.), Marathon 2 distinguishes itself with such features such as a rudimentary inventory system, ambient sound, multiple fire modes for each weapon, allies who aid the player, enemies belonging to different factions which will attack each other, a more developed plot (gradually narrated to the player at various computer terminals scattered throughout the levels).

The Xbox 360 version of the game presents a revised HUD and provides support for both 4-player split-screen play on the same console and 8-player Xbox Live gameplay. This version also supports 16:9 screen resolutions, high-definition output at 60 frames per second (compared to the original 30) as well as upgraded models and graphics

After your successful mission on the starship Marathon, you find yourself under the control of the rogue computer Durandal, who compels you to carry out tasks in a remote region of the galaxy. Your objective is to explore the remains of an ancient civilization, locate the remnants of a lost clan, and unveil their hidden knowledge. Prepare yourself for encounters with formidable and ancient adversaries, armed with advanced weaponry and cunning tactics. Throughout your journey, you must strive to survive the nightmarish alien environment and find a way to break free from Durandal's grip.