Missing In Action is a 3D action helicopter game that takes place during the Vietnam War. The game features a single player campaign which is divided into 26 missions, which are briefed by full motion videos with real life actors. Missions include finding MIAs, providing back-up for a damaged helicopter, destroying Vietcong camps or scouting an area. Each missions is action packed with many enemies that try to shoot you out of the air. The game features a radar that shows nearby enemy and friendly troops so that you know who to shoot.

Each mission you receive a new helicopter of a different type. Each new helicopter has more firepower than the previous one. It is also possible to call in artillery support, SEAL teams, napalm strikes and drop flare and smoke grenades.