Indigo Prophecy is an action-adventure game that involves the player in making decisions to alter the narrative. The name change in North America was made to avoid confusion with Michael Moore's Fahrenheit 9/11 documentary film, which was released in 2004. Indigo Prophecy introduced elements like ethical ambiguity, romance, the inability to perish, and interactive storytelling that would endure in Quantic Dream later games.

Without knowing why, Lucas Kane kills a man in a diner's restroom in New York City. Frightened, he contacts a spiritual medium, who helps him find out what happened the night of the murder. But what they find out doesn't only raise further questions, but puts everybody's life in danger.