Betrayal is the only installment in the series to be released on a non-PlayStation platform and presented as a 2D side-scrolling game. Despite the limitations of the mobile platform, in comparison to its home console counterparts, it retains the action-oriented approach of its predecessors, with the same combination of combo-based combat, platforming, and puzzle game elements. Although God of War is primarily a home console series, Betrayal was praised for its fidelity to the series in terms of gameplay, art style, and graphics: "the real deal third game in the killer franchise".

It received awards for "Wireless Game of the Month" (June 2007) and "Best Platform Game" (wireless) of 2007.

Following the events of God of War, Kratos is leading his Spartan army against Greece. While fighting alongside his warriors, he is attacked by a number of beasts led by the giant, Argos, who is sent by Hera to stop the war Kratos is waging. However, before Kratos is able to kill the beast, it is killed by an unknown assassin as a clear effort to destroy the anti-hero's reputation with the Gods of Olympus. Kratos pursues him through Greece in order to discover the identity of the assassin's master, who is attempting to turn the gods against him. However, he is being slowed down by an attack of Hades' minions. Soon, the son of Hermes, Ceryx, is sent to deliver a message to Kratos from Zeus, who's becoming increasingly concerned with the amount of destruction left in Kratos' path. Ceryx confronts Kratos, but the God of War refuses to cease and engages the messenger in battle. Taking advantage of the situation, the assassin escapes. The game concludes as Kratos kills Ceryx and the Spartan soldiers celebrate, but observing the dead god's body, he realizes that Zeus would eventually take action for this act of defiance.