The game is a normal Point & Click adventure where you've to find items with which you can solve the riddles in the game and talk to various characters (some already known to the readers of the comic). But since Mortadelo and Filemón are a team, you can always switch between both characters. Everyone has different abilities. For example Mortadelo can disguise himself to distract someone while Filemón steals an item from the person.

As a feature, never seen in an adventure before, there's also a multiplayer-mode available where one person takes control over Mortadelo and the other over Filemón.

When Dr. Bacterio tests his new invention with which he can extract anything from movies and make it a real object, he doesn't bring out the famous treasure of the mummy but the mummy Impoteh himself. Since he's a little cranky and wants to take over the world, beginning with the basement of the T.I.A headquarter, Mortadelo and Filemón have to stop him. To do so, they need to enter Dr. Bacterio's machine and get the book of the dead. But since nothing is perfect, they don't land in the right movie and so they've to make their way through several other movies where they meet famous actors like Charlie Chaplin, John Wayne or Humphrey Bogart.