Advanced Variable Geo 2 is one of several titles in the long-running all-girl fighting game series. Using one of 12 characters, including nine returning from the previous title, the player can choose from a variety mode, including a standard arcade mode, a story mode, a 2-player versus mode, and a time attack mode. There is also a practice mode, a wide variety of game options, and play statistics tracking.

The sequel to Advanced V.G. centers around a plot-driven "Story Mode" which features new protagonist Tamao Mitsurugi facing all of the previous competitors, as well as new faces Kyoko Kirishima and Saki Shinjou before going on to face the new boss characters Material and Miranda Jahana, Reimi's mother.