This game is the sequel to Adarna, which was released in the year 2015.

In the original 17th century Ibong Adarna tale by Jose de la Cruz, the Princesses Maria Blanca, Juana and Leonora were merely the girlfriends of the protagonist Prince Juan. At the end of the corrido, Juan picks Maria Blanca as his preferred wife, while the other two women became the wives of Juan's brothers, Pedro and Diego. All three women had interesting backgrounds, but the way they were treated in the story left something to be desired. This is a manuscript that is often discussed in Filipino literature classes, but the portrayal of women — either as damsels in distress or prizes to be chosen — are not empowering.

Adarna: The Legend of Maria Blanca re-imagines what it would be like if these princesses' lives did not revolve around Juan or his brothers. Many regions of pre-Hispanic Philippines had matriarchal societies, and while the first Adarna game released by Senshi.Labs had a very Western feel to it, this sequel attempts to transport the players back to an indigeous pre-colonial atmosphere while keeping the language somewhat up to date.

This adventure starts off in the Kingdom of Reinos de los Kristales, where the Princess Maria Blanca learns that her sister Isabela has fallen ill. A hermit approaches Maria to inform her that Isabela can only be cured by the mythical creature of Adarna. Maria then slips away from the kingdom and embarks on a quest to find the legendary bird.